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Home >> Antibodies >> Beta Defensin 1 Antibody / DEFB1

Beta Defensin 1 Antibody / DEFB1 (R30522)

  Catalog No Formulation Size Price (USD)  
Image R30522 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 389
Western blot testing of Defensin 1 antibody and human COLO320 lysate; Predicted molecular weight ~7 kDa.
IHC-P: beta Defensin 1 antibody testing of lung cancer tissue
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P60022
Localization Secreted
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This beta Defensin 1 antibody is available for research use only.
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Description

Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1 gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1 may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the beta Defensin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human beta Defensin 1 (FTKIQGTCYRGKAKCCK) was used as the immunogen for this beta Defensin 1 antibody.

Storage

After reconstitution, the beta Defensin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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