- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Beta Catenin Antibody (C-Terminal Region) [clone 691CT11.2.1] (F54099)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F54099-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 439 | |
|
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F54099-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 205 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat, Monkey |
| Predicted Reactivity | Bovine |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | 691CT11.2.1 |
| Purity | Protein G purified |
| UniProt | P35222 |
| Applications | Western Blot : 1:4000 |
| Limitations | This Beta Catenin antibody is available for research use only. |
|
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Beta Catenin / CTNNB1 is a key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.
This CTNNB1 antibody complements our Beta-Catenin Antibody / CTNNB1 Antibody (clone CTNNB1/2030R) for broader analysis of CTNNB1 expression and localization.
The stated application concentrations are suggested starting points. Titration of the Beta Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 687-721 from human Beta Catenin was used as the immunogen for the Beta Catenin antibody.
Aliquot the Beta Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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