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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
Optimal dilution of the Beta Amyloid antibody should be determined by the researcher.
A portion of amino acids 578-680 from the human protein was used as the immunogen for the Beta Amyloid antibody.
Store the Beta Amyloid antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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