- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
BCOR Antibody / BCL-6 Corepressor (F54442)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54442-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54442-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q6W2J9 |
| Applications | Western blot : 1:500-1:2000 Flow cytometry : 1:25 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:25 |
| Limitations | This BCOR antibody is available for research use only. |
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BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
The stated application concentrations are suggested starting points. Titration of the BCOR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1107-1137 from the human protein was used as the immunogen for the BCOR antibody.
Aliquot the BCOR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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