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Home >> Antibodies >> BCL10 Antibody

BCL10 Antibody [clone 1185CT13.2.1.2] (F54525)

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  Catalog No Formulation Size Price (USD)  
Image F54525-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F54525-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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IHC testing of FFPE human kidney tissue with BCL10 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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IHC testing of FFPE human kidney tissue with BCL10 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
IHC testing of FFPE mouse kidney tissue with BCL10 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of human Daudi cell lysate with BCL10 antibody. Expected molecular weight: 26~33 kDa.
Flow cytometry testing of human HeLa cells with BCL10 antibody; Blue=isotype control, Green= BCL10 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype IgG1, kappa
Clone Name 1185CT13.2.1.2
Purity Protein G affinity
UniProt O95999
Localization Nuclear, cytoplasmic
Applications Immunohistochemistry (FFPE) : 1:25
Flow Cytometry : 1:25 (1x10e6 cells)
Western Blot : 1:500-1:2000
Limitations This BCL10 antibody is available for research use only.
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Description

Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Application Notes

The stated application concentrations are suggested starting points. Titration of the BCL10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Recombinant human protein was used as the immunogen for the BCL10 antibody.

Storage

Aliquot the BCL10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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