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Home >> Antibodies >> BAX Antibody

BAX Antibody (F52764)

  Catalog No Formulation Size Price (USD)  
Image F52764-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 379
Image
F52764-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 155
Western blot analysis of lysate from 1) HeLa, 2) 293, 3) HT-1080, 4) Raji, 5) SH-SY5Y and 6) THP-1 cell line using BAX antibody at 1:1000.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q07812
Applications Western blot : 1:1000
Limitations This BAX antibody is available for research use only.
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Description

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Application Notes

Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This BAX antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX.

Storage

Aliquot the BAX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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