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Home >> Antibodies >> BANP Antibody

BANP Antibody [clone 1524CT337.6.32] (F53808)

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  Catalog No Formulation Size Price (USD)  
Image F53808-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53808-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of human HeLa cell lysate with BANP antibody at 1:1000. Predicted molecular weight: 56 kDa, observed here at ~70 kDa.
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Western blot testing of human HeLa cell lysate with BANP antibody at 1:1000. Predicted molecular weight: 56 kDa, observed here at ~70 kDa.
IHC testing of FFPE human breast carcinoma with BANP antibody at 1:25. HIER: steamed in pH6 citrate buffer.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 1524CT337.6.32
Purity Protein G affinity chromatography
UniProt Q8N9N5
Applications Western blot : 1:500-1000
IHC (FFPE) : 1:25
Limitations This BANP antibody is available for research use only.
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  • Applications : WB
    Reactivity : Human
    Pred. Reactivity : Mouse, Bovine

Description

Btg3-associated nuclear protein controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Application Notes

Titration of the BANP antibody may be required due to differences in protocols and substrate sensitivity.

Immunogen

A human recombinant protein of amino acids 30-390 was used as the immunogen for the BANP antibody.

Storage

Aliquot the BANP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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