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Home >> Antibodies >> Bag-1 Antibody [Discontinued, view alternative antibodies]

Bag-1 Antibody [Discontinued, view alternative antibodies] (R30463)

  Catalog No Formulation Size Price (USD)  
Image R30463 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of Bag-1 antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng; 4: human MCF-7 cell lysate. Predicted molecular weight ~39 kDa.
IHC-P: Bag-1 antibody testing of rat intestine tissue
Availability Discontinued
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q99933
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Immunocytochemistry : 0.5-1ug/ml
Limitations This Bag-1 antibody is available for research use only.
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Description

Bcl-2-associated athanogene 1 is a protein that in humans is encoded by the BAG1 gene, mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag-1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Bag-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Bag-1 (DTVEQNICQETERLQSTNFALAE) was used as the immunogen for this Bag-1 antibody.

Storage

After reconstitution, the Bag-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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