- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
BACE Antibody (F50757)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F50757-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F50757-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Predicted Reactivity | Rat, Bovine |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P56817 |
| Applications | Western blot : 1:1000 |
| Limitations | This BACE antibody is available for research use only. |
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.
Aliquot the BACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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