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Home >> Antibodies >> BACE Antibody

BACE Antibody (F50757)

  Catalog No Formulation Size Price (USD)  
Image F50757-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50757-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of BACE antibody and mouse cerebellum tissue lysate.
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Rat, Bovine
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P56817
Applications Western blot : 1:1000
Limitations This BACE antibody is available for research use only.
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Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.

Application Notes

Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.

Storage

Aliquot the BACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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