• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> B-cell lymphoma/leukemia 11A Antibody / BCL11A

B-cell lymphoma/leukemia 11A Antibody / BCL11A [clone PCRP-BCL11A-1H3] (V9714)

  Catalog No Formulation Size Price (USD)  
Image V9714-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
Image
V9714-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
Image
V9714SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
Bulk quote request
FACS staining of PFA-fixed human HeLa cells with B-cell lymphoma/leukemia 11A antibody (blue, clone PCRP-BCL11A-1H3) and isotype control (red).
Immunofluorescent staining of PFA-fixed human MCF-7 cells using B-cell lymphoma/leukemia 11A antibody (green, clone PCRP-BCL11A-1H3) and phalloidin (red).
SDS-PAGE analysis of purified, BSA-free B-cell lymphoma/leukemia 11A antibody (clone PCRP-BCL11A-1H3) as confirmation of integrity and purity.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using B-cell lymphoma/leukemia 11A antibody (clone PCRP-BCL11A-1H3). These results demonstrate the foremost specificity of the PCRP-BCL11A-1H3 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name PCRP-BCL11A-1H3
Purity Protein A/G affinity
UniProt Q9H165
Localization Cytoplasm, Nucleus
Applications ELISA (order BSA-free format for coating) :
Flow cytometry : 1-2ug/million cells
Immunofluorescence : 1-2ug/ml
Limitations This B-cell lymphoma/leukemia 11A antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Application Notes

Optimal dilution of the B-cell lymphoma/leukemia 11A antibody should be determined by the researcher.

Immunogen

Recombinant full-length human protein was used as the immunogen for the B-cell lymphoma/leukemia 11A antibody.

Storage

Aliquot the B-cell lymphoma/leukemia 11A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.