- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
b-Catenin Antibody [clone 9F2] (V3210)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V3210-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 519 | |
|
|
V3210-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 229 | |
|
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V3210SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | 9F2 |
| Purity | Protein G affinity chromatography |
| UniProt | P35222 |
| Localization | Cell surface, cytoplasmic, cell junctions |
| Applications | Flow cytometry : 0.5-1ug/10^6 cells Immunofluorescence : 1-2ug/ml Western blot : 0.5-1ug/ml |
| Limitations | This b-Catenin antibody is available for research use only. |
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The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]
Titration of the b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.
Store the b-Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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