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Home >> Antibodies >> AURKC Antibody

AURKC Antibody (F53762)

  Catalog No Formulation Size Price (USD)  
Image F53762-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F53762-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot testing of AURKC antibody and A375 cell lysate. Predicted molecular weight ~ 33 kDa.
IHC analysis of FFPE human breast carcinoma tissue stained with the AURKC antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9UQB9
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This AURKC antibody is available for research use only.
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Description

Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Application Notes

Titration of the AURKC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of the C-terminal region of the human protein was used as immunogen for this AURKC antibody.

Storage

Aliquot the AURKC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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