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Home >> Antibodies >> ATXN3 Antibody

ATXN3 Antibody (F55027)

  Catalog No Formulation Size Price (USD)  
Image F55027-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 359
Image
F55027-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt P54252
Applications Western blot : 1:500-1:2000
Flow cytometry : 1:25 (1x10e6 cells)
Immunohistochemistry (FFPE) : 1:25
Limitations This ATXN3 antibody is available for research use only.
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Description

ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.

Application Notes

The stated application concentrations are suggested starting points. Titration of the ATXN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 261-288 from the human protein was used as the immunogen for the ATXN3 antibody.

Storage

Aliquot the ATXN3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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