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Home >> Antibodies >> Atrogin 1 Antibody / FBXO32

Atrogin 1 Antibody / FBXO32 (F53855)

  Catalog No Formulation Size Price (USD)  
Image F53855-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 329
Image
F53855-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 135
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with Atrogin 1 antibody at 1:2000. Predicted molecular weight: 42 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Bovine, Pig
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q969P5
Applications Western blot : 1:1000-2000
Limitations This Atrogin 1 antibody is available for research use only.
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Description

F-box only protein 32 / Atrogin 1 is a substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.

Application Notes

Titration of the Atrogin 1 antibody may be required due to differences in protocols and substrate sensitivity.

Immunogen

A portion of amino acids 17-49 from the human protein was used as the immunogen for the Atrogin 1 antibody.

Storage

Aliquot the Atrogin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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