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Home >> Antibodies >> ATG7 Antibody

ATG7 Antibody [clone FCA-1] (RQ4806)

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  Catalog No Formulation Size Price (USD)  
Image RQ4806 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HepG2 cell lysate with ATG7 antibody. Predicted molecular weight: 70-80 kDa.
Western blot testing of human HepG2 cell lysate with ATG7 antibody. Predicted molecular weight: 70-80 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name FCA-1
Purity Affinity purified
UniProt O95352
Applications Western blot : 1:10000-1:50000
Limitations This ATG7 antibody is available for research use only.
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Description

ATG7 is an E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. [UniProt]

Application Notes

Optimal dilution of the ATG7 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human ATG7 was used as the immunogen for the ATG7 antibody.

Storage

Store the ATG7 antibody at -20oC.

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