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ATG7 is an E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. [UniProt]
Optimal dilution of the ATG7 antibody should be determined by the researcher.
A synthetic peptide specific to human ATG7 was used as the immunogen for the ATG7 antibody.
Store the ATG7 antibody at -20oC.
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