- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ATF2 Antibody / Activating Transcription Factor 2 [clone IA-1] (RQ5447)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5447 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | IA-1 |
| Purity | Affinity purified |
| UniProt | P15336 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This ATF2 antibody is available for research use only. |
|
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The ATF2 gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. [RefSeq]
Optimal dilution of the ATF2 antibody should be determined by the researcher.
A synthetic peptide specific to human Activating Transcription Factor 2 was used as the immunogen for the ATF2 antibody.
Store the ATF2 antibody at -20oC.
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