- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Ataxin 3 Antibody / ATXN3 (F55027)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F55027-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 379 | |
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F55027-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 165 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | P54252 |
| Localization | Nuclear |
| Applications | Western blot : 1:500-1:1000 Flow cytometry : 1:10-1:50 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:50-1:100 |
| Limitations | This Ataxin 3 antibody is available for research use only. |
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ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
The stated application concentrations are suggested starting points. Titration of the Ataxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 261-288 from the human protein was used as the immunogen for the Ataxin 3 antibody.
Aliquot the Ataxin 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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