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Home >> Antibodies >> ASIC4 Antibody / ACCN4

ASIC4 Antibody / ACCN4 (F44840)

  Catalog No Formulation Size Price (USD)  
Image F44840-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F44840-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
ASIC4 antibody western blot analysis in human HepG2 lysate. Predicted molecular weight ~70 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q96FT7
Applications Western blot : 1:1000
Limitations This ASIC4 antibody is available for research use only.
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Description

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.

Application Notes

Titration of the ASIC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 23-52 from the human protein was used as the immunogen for this ASIC4 antibody.

Storage

Aliquot the ASIC4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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