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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Amiloride-sensitive cation channel 1, neuronal, also known as ASIC2,is a protein that in humans is encoded by the ACCN1 gene. This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
Optimal dilution of the ASIC2 antibody should be determined by the researcher.
Recombinant human protein (amino acids H27-C512) was used as the immunogen for the ASIC2 antibody.
After reconstitution, the ASIC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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