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Home >> Antibodies >> ASIC1 Antibody / ACCN2

ASIC1 Antibody / ACCN2 (F51622)

  Catalog No Formulation Size Price (USD)  
Image F51622-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 359
Image
F51622-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
Western blot analysis of ASIC1 antibody and human CEM lysate. Predicted molecular weight ~59 kDa.
IHC analysis of FFPE human brain tissue stained with ASIC1 antibody
ASIC1 antibody flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control (top histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Chicken, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P78348
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This ASIC1 antibody is available for research use only.
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Description

ACCN2 / ASIC1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.

Application Notes

Titration of the ASIC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 500-526 from the human protein was used as the immunogen for this ASIC1 antibody.

Storage

Aliquot the ASIC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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