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- Tel: 858.663.9055
- Email: info@nsjbio.com
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
Titration of the ASAH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 734-762 from the human protein was used as the immunogen for this ASAH2 antibody.
Aliquot the ASAH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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