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Home >> Antibodies >> ASAH2 Antibody

ASAH2 Antibody (F40044)

  Catalog No Formulation Size Price (USD)  
Image F40044-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F40044-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
ASAH2 antibody western blot analysis in mouse bladder tissue lysate
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NR71
Applications Western blot : 1:1000
Limitations This ASAH2 antibody is available for research use only.
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Description

Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).

Application Notes

Titration of the ASAH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 734-762 from the human protein was used as the immunogen for this ASAH2 antibody.

Storage

Aliquot the ASAH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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