Aryl hydrocarbon Receptor Antibody / AHR (R30876)

Aryl Hydrocarbon Receptor Antibody Gastric Cancer IHC. Immunohistochemical staining of FFPE human gastric cancer tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that integrates signals from xenobiotics, dietary metabolites, and inflammatory pathways to regulate gene expression and cellular homeostasis. Predominantly nuclear and cytoplasmic staining is observed throughout malignant cells, consistent with active AHR signaling and its emerging role in tumor progression and metabolic adaptation. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These findings support the utility of AHR Antibody for studies of cancer biology, toxicology, and transcriptional regulation.

Aryl Hydrocarbon Receptor Antibody Lymphadenoma IHC. Immunohistochemical staining of FFPE human lymphadenoma tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that regulates immune cell differentiation, inflammatory signaling, and cellular responses to endogenous and environmental ligands. Diffuse nuclear and cytoplasmic staining is observed throughout the lymphoid tumor cells, consistent with the established role of AHR in modulating immune homeostasis and hematopoietic cell function. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These results support the utility of AHR Antibody for studies of immunology, lymphoid malignancies, and signal transduction pathways.

Aryl Hydrocarbon Receptor Antibody Placenta IHC. Immunohistochemical staining of FFPE human placental tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that regulates xenobiotic metabolism, immune tolerance, and developmental signaling pathways. Prominent nuclear and cytoplasmic staining is observed in trophoblastic cells lining the chorionic villi, consistent with the established role of AHR in placental development and maintenance of the maternal fetal interface. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These results support the utility of AHR Antibody for studies of reproductive biology, developmental signaling, and environmental response mechanisms.

Aryl Hydrocarbon Receptor Antibody Mouse Brain IHC. Immunohistochemical staining of FFPE mouse brain tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that integrates signals from dietary metabolites, microbiota derived compounds, and environmental ligands to regulate neurodevelopment and immune homeostasis. Scattered nuclear and cytoplasmic staining is observed in neuronal and glial populations, with increased reactivity in cells adjacent to the ventricular surface, consistent with the emerging role of AHR in central nervous system function and neuroinflammatory signaling. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These results support the utility of AHR Antibody for studies of neurobiology, environmental sensing, and transcriptional regulation.

Aryl Hydrocarbon Receptor Antibody Cerebellum IHC. Immunohistochemical staining of FFPE mouse brain tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that regulates responses to endogenous metabolites and environmental stimuli. Distinct nuclear staining is observed in linear arrays of cells within the cerebellar white matter and adjacent neuronal layers, consistent with the expression of AHR in specialized neural and glial populations involved in maintaining central nervous system homeostasis. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These findings support the utility of AHR Antibody for investigations of neurodevelopment, neuroinflammation, and transcriptional responses to environmental cues.

Aryl Hydrocarbon Receptor Antibody Rat Brain IHC. Immunohistochemical staining of FFPE rat brain tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that integrates signals from endogenous metabolites, dietary compounds, and environmental toxicants to regulate gene expression and immune responses. Widespread nuclear staining is observed throughout neuronal populations and scattered glial cells, reflecting the role of AHR in maintaining neural homeostasis and modulating neuroinflammatory pathways. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These results support the utility of AHR Antibody for studies of neurobiology, transcriptional regulation, and environmental sensing mechanisms.

Aryl Hydrocarbon Receptor Antibody Hippocampus IHC. Immunohistochemical staining of FFPE rat brain tissue demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that regulates xenobiotic responses, immune signaling, and neuronal homeostasis. Prominent nuclear staining is observed within densely packed neuronal layers of the hippocampal formation, while scattered positive cells are present throughout the surrounding parenchyma. This distribution is consistent with emerging roles for AHR in neurodevelopment, synaptic plasticity, and responses to endogenous metabolic cues. Heat induced epitope retrieval was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These findings support the utility of AHR Antibody for studies of neurobiology, environmental sensing, and transcriptional regulation.

Aryl Hydrocarbon Receptor Antibody A431 Cells IF. Immunofluorescent staining of FFPE human A431 cells demonstrates AHR expression using an Aryl Hydrocarbon Receptor antibody (green). AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that translocates to the nucleus following activation by endogenous metabolites and xenobiotic ligands. Strong nuclear fluorescence is observed, consistent with the role of AHR in regulating transcriptional responses and cellular adaptation to environmental stimuli. DAPI nuclear stain identifies cell nuclei (blue). Heat induced epitope retrieval was performed by steaming sections in pH 6 citrate buffer for 20 minutes prior to staining. These results support the utility of AHR Antibody for studies of toxicology, signal transduction, and transcriptional regulation.

Aryl Hydrocarbon Receptor Antibody Human Cell Lines WB. Western blot analysis of AHR expression using an Aryl Hydrocarbon Receptor antibody. Lane 1: human HeLa cell lysate. Lane 2: human PC-3 cell lysate. Lane 3: human Caco-2 cell lysate. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that regulates xenobiotic metabolism and cellular responses to endogenous and environmental ligands. A prominent band is detected at approximately 95 kDa in all three cell lines, corresponding to the expected molecular weight of full length AHR. Stronger expression is observed in Caco-2 cells, consistent with the important role of AHR in intestinal barrier function and metabolic signaling. These results support the utility of AHR Antibody for studies of toxicology, immune regulation, and signal transduction.

Aryl Hydrocarbon Receptor Antibody A431 Cells FACS. Flow cytometric analysis of human A431 cells was performed using an Aryl Hydrocarbon Receptor antibody at 1 ug per million cells following blocking with goat sera. AHR, also known as an Environmental Sensor Protein, is a ligand activated transcription factor that mediates cellular responses to xenobiotics, microbial metabolites, and endogenous signaling molecules. Red histogram: cells alone. Green histogram: isotype control. Blue histogram: Aryl Hydrocarbon Receptor antibody. The pronounced rightward shift of the AHR antibody signal relative to the controls demonstrates specific detection of endogenous AHR expression in A431 cells. These results support the utility of AHR Antibody for studies of toxicology, immune regulation, environmental sensing, and signal transduction pathways.