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Home >> Antibodies >> Aromatase Antibody / CYP19A1

Aromatase Antibody / CYP19A1 [clone AABB-3] (RQ5368)

  Catalog No Formulation Size Price (USD)  
Image RQ5368 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of rat brain lysate with Aromatase antibody. Predicted molecular weight ~58 kDa.
Availability 1-2 weeks
Species Reactivity Human, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AABB-3
Purity Affinity purified
UniProt P11511
Applications Western blot : 1:500-1:2000
Limitations This Aromatase antibody is available for research use only.
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Description

The CYP19A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [RefSeq]

Application Notes

Optimal dilution of the Aromatase antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Aromatase / CYP19A1 was used as the immunogen for the Aromatase antibody.

Storage

Store the Aromatase antibody at -20oC.

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