AKR1C2 Antibody / Hormone Metabolism Enzyme Antibody [clone CPTC-AKR1C2-1] (V7715)

AKR1C2 Antibody Prostate Carcinoma IHC. Immunohistochemistry analysis of FFPE human prostate carcinoma tissue using AKR1C2 Antibody (clone CPTC-AKR1C2-1) shows cytoplasmic staining in tumor epithelial cells, consistent with AKR1C2 / Aldo-keto reductase family 1 member C2 localization as a cytosolic enzyme involved in hormone metabolism. The staining outlines glandular tumor structures with variable intensity across the tumor field, while surrounding stromal regions display comparatively lower signal. Hematoxylin counterstain provides nuclear contrast and tissue architecture. HIER: boil FFPE tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min and allow to cool before testing.

AKR1C2 Antibody Prostate Tumor Gland IHC. Immunohistochemistry analysis of FFPE human prostate carcinoma tissue using AKR1C2 Antibody (clone CPTC-AKR1C2-1) shows cytoplasmic staining in tumor epithelial cells lining glandular structures, consistent with AKR1C2 / Aldo-keto reductase family 1 member C2 localization as a cytosolic enzyme involved in hormone metabolism. The staining highlights glandular architecture with moderate intensity across epithelial cells, while surrounding stromal regions display comparatively lower signal. Hematoxylin counterstain provides nuclear contrast and tissue context. HIER: boil FFPE tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min and allow to cool before testing.

AKR1C2 Antibody Human Cell Line Panel WB. Western blot analysis of human HeLa, K562, and A431 cell lysates using AKR1C2 Antibody (clone CPTC-AKR1C2-1) detects a band at approximately 37 kDa, consistent with the predicted molecular weight of AKR1C2 / Aldo-keto reductase family 1 member C2. The banding pattern across multiple cell lines supports reliable detection of this cytosolic enzyme, aligning with its role in hormone metabolism and steroid regulation pathways.

AKR1C2 Antibody Multi-Species Liver WB. Western blot analysis of (1) human liver, (2) mouse liver, (3) rat liver, (4) hamster liver, (5) guinea pig liver, and (6) HepG2 cell lysates using AKR1C2 Antibody (clone CPTC-AKR1C2-1) detects a band at approximately 37 kDa in human liver and HepG2 samples, consistent with the predicted molecular weight of AKR1C2 / Aldo-keto reductase family 1 member C2. Signal is not observed in the other species tested, indicating selective species reactivity for this clone. The pattern supports targeted detection of AKR1C2 in human-derived hepatic models, aligning with its role in hormone metabolism and steroid regulation pathways.

SDS-PAGE analysis of purified, BSA-free AKR1C2 antibody (clone CPTC-AKR1C2-1) as confirmation of integrity and purity.