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Home >> Antibodies >> ARK1C1 Antibody / Aldo-keto Reductase Family 1 Member C1

ARK1C1 Antibody / Aldo-keto Reductase Family 1 Member C1 [clone AKR1C1/9063] (V5582)

  Catalog No Formulation Size Price (USD)  
Image V5582-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V5582-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V5582SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of human liver tissue lysate using AKR1C1 antibody (clone AKR1C1/9063). Predicted molecular weight ~37 kDa.
Western blot testing of human HepG2 cell lysate using AKR1C1 antibody (clone AKR1C1/9063). Predicted molecular weight ~37 kDa.
IHC staining of FFPE human hepatocellular carcinoma with ARK1C1 antibody (clone AKR1C1/9063). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free ARK1C1 antibody (clone AKR1C1/9063) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name AKR1C1/9063
Purity Protein A/G affinity
UniProt Q04828
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Western blot : 2-4ug/ml
Limitations This ARK1C1 antibody is available for research use only.
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Description

DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Application Notes

Optimal dilution of the ARK1C1 antibody should be determined by the researcher.

Immunogen

Recombinant human full-length AKR1C1 protein was used as the immunogen for the ARK1C1 antibody.

Storage

Aliquot the ARK1C1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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