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Home >> Antibodies >> Ark-1 Antibody / Aurora-related kinase 1 / Aurka

Ark-1 Antibody / Aurora-related kinase 1 / Aurka (RQ7273)

  Catalog No Formulation Size Price (USD)  
Image RQ7273 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
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Western blot testing of 1) rat testis, 2) mouse testis, 3) mouse thymus and 4) mouse HEPA1-6 cell lysate with Ark-1 antibody. Predicted molecular weight ~45 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P97477
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Ark-1 antibody is available for research use only.
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AURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A / Aurora-related kinase 1 is a member of a family of mitotic serine/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.

Application Notes

Optimal dilution of the Ark-1 antibody should be determined by the researcher.


Recombinant mouse protein (amino acids M1-S395) was used as the immunogen for the Ark-1 antibody.


After reconstitution, the Ark-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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