- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Ark-1 Antibody / Aurora-related kinase 1 / Aurka (RQ7273)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ7273 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | P97477 |
| Applications | Western blot : 0.5-1ug/ml Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This Ark-1 antibody is available for research use only. |
|
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AURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A / Aurora-related kinase 1 is a member of a family of mitotic serine/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.
Optimal dilution of the Ark-1 antibody should be determined by the researcher.
Recombinant mouse protein (amino acids M1-S395) was used as the immunogen for the Ark-1 antibody.
After reconstitution, the Ark-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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