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Home >> Antibodies >> Arginase 1 Antibody / ARG1

Arginase 1 Antibody / ARG1 [clone ARG1/9446] (V5753)

  Catalog No Formulation Size Price (USD)  
Image V5753-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5753-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5753SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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Western blot testing of human liver tissue lysate with Arginase 1 antibody (clone ARG1/9446). Predicted molecular weight ~35 kDa.
SDS-PAGE analysis of purified, BSA-free Arginase 1 antibody (clone ARG1/9446) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name ARG1/9446
Purity Protein G affinity
UniProt P05089
Localization Cytoplasm
Applications Western Blot : 2-4ug/ml
Limitations This Arginase-1 antibody is available for research use only.
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Description

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Application Notes

Optimal dilution of the Arginase-1 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 1-200 from human ARG1 proteinwas used as the immunogen for the Arginase-1 antibody.

Storage

Aliquot the Arginase-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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