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Home >> Antibodies >> Arginase 1 Antibody

Arginase 1 Antibody [clone ARG1/6790R] (V8793)

  Catalog No Formulation Size Price (USD)  
Image V8793-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 499
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V8793-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 219
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V8793SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 499
Western blot analysis of human liver tissue lysate using Arginase 1 antibody (clone ARG1/6790R). Predicted molecular weight ~35 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ARG1/6790R
Purity Protein A/G affinity
UniProt P05089
Localization Cytoplasmic
Applications Western blot : 1-2ug/ml
Limitations This Arginase 1 antibody is available for research use only.
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Description

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Application Notes

Optimal dilution of the Arginase 1 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 300-400 was used as the immunogen for the Arginase 1 antibody.

Storage

Aliquot the Arginase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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