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Home >> Antibodies >> ARGBP2 Antibody

ARGBP2 Antibody (F54906)

  Catalog No Formulation Size Price (USD)  
Image F54906-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 359
Image
F54906-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O94875
Applications Western blot : 1:500-1:2000
Immunofluorescence : 1:25
Immunohistochemistry (FFPE) : 1:25
Flow cytometry : 1:25 (1x10e6 cells)
Limitations This ARGBP2 antibody is available for research use only.
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Description

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

Application Notes

The stated application concentrations are suggested starting points. Titration of the ARGBP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 175-204 from the human protein was used as the immunogen for the ARGBP2 antibody.

Storage

Aliquot the ARGBP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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