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- Email: info@nsjbio.com
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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
Titration of the ARG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 293-322 from the human protein was used as the immunogen for this ARG1 antibody.
Aliquot the ARG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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