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Home >> Antibodies >> ARD1A Antibody / NAA10

ARD1A Antibody / NAA10 (F53909)

  Catalog No Formulation Size Price (USD)  
Image F53909-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 329
Image
F53909-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 135
Western blot testing of human 1) SK-BR-3, 2) HeLa, 3) HCT116, 4) MCF-7 and 5) HL-60 cell lysate with NAA10 antibody at 1:2000. Predicted molecular weight: 26 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P41227
Applications Western blot : 1:1000-2000
Limitations This NAA10 antibody is available for research use only.
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Description

N-alpha-acetyltransferase 10 is the catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.

Application Notes

Titration of the NAA10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 135-167 from the human protein was used as the immunogen for the NAA10 antibody.

Storage

Aliquot the NAA10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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