- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
AR Antibody (F42850)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F42850-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F42850-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P10275 |
| Applications | Western blot : 1:1000 |
| Limitations | This AR antibody is available for research use only. |
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The androgen receptor, also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. It is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.
The main function of the AR is as a DNA-binding transcription factor that regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. [Wiki]
Titration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 475-504 from the human protein was used as the immunogen for this AR antibody.
Aliquot the AR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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