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Home >> Antibodies >> Aquaporin 7 Antibody [Discontinued, view alternative antibodies]

Aquaporin 7 Antibody [Discontinued, view alternative antibodies] (R31205)

  Catalog No Formulation Size Price (USD)  
Image R31205 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of Aquaporin 7 antibody and Lane 1: SGC; 2: SMMC-7721; 3: A549; 4: COLO320 cell lysate
Availability Discontinued
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt O14520
Applications Western blot : 0.5-1ug/ml
Limitations This Aquaporin 7 antibody is available for research use only.
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Description

Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene. The gene is composed of six exons distributing over 6.5 kb. The exon-intron boundaries are identical to those of the human AQP3 gene. The intron sizes are also similar. Moreover, chromosomal localization of AQP7 was assigned to 9p13 by fluorescent in situ hybridization, where AQP3 is also localized, suggesting that 9p13 may be another site of an aquaporin cluster. AQP7 acts as a glycerol facilitator in cardiomyocytes and that glycerol is a substrate for cardiac energy production. AQP7 is down-regulated in women with severe obesity. The expression of this glycerol channel is not affected by type 2 diabetes.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Aquaporin 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminus of human Aquaporin 7 (AKIQEILQRKMVREFLAEFM) was used as the immunogen for this Aquaporin 7 antibody.

Storage

After reconstitution, the Aquaporin 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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