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Home >> Antibodies >> Apoptosis inhibitor 5 Antibody

Apoptosis inhibitor 5 Antibody (R30177)

  Catalog No Formulation Size Price (USD)  
Image R30177 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of Apoptosis Inhibitor 5 antibody and Lane 1: rat heart; 2: rat brain; 3: rat testis; 4: rat placenta; 5: MCF-7; 6: HeLa; 7: CEM; 8: SMMC-7721; 9: COLO320 cell lysate
IHC-P: Apoptosis Inhibitor 5 antibody testing of rat brain tissue
ICC testing of HeLa cells
IHC-F testing of rat heart tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q9BZZ5
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
IHC (Frozen) : 0.5-1ug/ml
Immunocytochemistry : 0.5-1ug/ml
Limitations This Apoptosis inhibitor 5 antibody is available for research use only.
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Description

Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death(apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Apoptosis inhibitor 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Apoptosis inhibitor 5 (amino acids 487-504 of isoform b, KYSSNLGNFNYERSLQGK) was used as the immunogen for this Apoptosis inhibitor 5 antibody.

Storage

After reconstitution, the Apoptosis inhibitor 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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