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Home >> Antibodies >> Apolipoprotein B Antibody / APOB

Apolipoprotein B Antibody / APOB [clone AOIH-1] (RQ5037)

  Catalog No Formulation Size Price (USD)  
Image RQ5037 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human serum lysate with Apolipoprotein B antibody. Predicted molecular weight ~516 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOIH-1
Purity Affinity purified
UniProt P04114
Applications Western blot : 1:500-1:2000
Limitations This Apolipoprotein B antibody is available for research use only.
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Description

The APOB gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 (~240 kDa) and apoB-100 (~516 kDa): the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. [RefSeq]

Application Notes

Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Apolipoprotein B / APOB was used as the immunogen for the Apolipoprotein B antibody.

Storage

Store the Apolipoprotein B antibody at -20oC.

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