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Home >> Antibodies >> AP2 Antibody

AP2 Antibody (F47549)

  Catalog No Formulation Size Price (USD)  
Image F47549-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F47549-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
AP2 antibody western blot analysis in U251 lysate. Predicted molecular weight ~47 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P05549
Applications Western blot : 1:1000
Limitations This AP2 antibody is available for research use only.
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Description

Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Application Notes

Titration of the AP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody.

Storage

Aliquot the AP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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