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Home >> Antibodies >> Anti-UchL1 Antibody

Anti-UchL1 Antibody [clone SPM575] (V9097)

  Catalog No Formulation Size Price (USD)  
Image V9097-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 429
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V9097-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 199
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V9097SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 429
Western blot testing of human brain lysate with anti-UchL1 antibody (clone SPM575). Predicted molecular weight ~25 kDa.
SDS-PAGE analysis of purified, BSA-free anti-UchL1 antibody (clone SPM575) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name SPM575
Purity Protein G affinity chromatography
UniProt P09936
Localization Cytoplasmic. Endoplasmic Reticulum membrane
Applications Western blot : 1-2ug/ml
Limitations This anti-UchL1 antibody is available for research use only.
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Description

This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, UchL1 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for UchL1 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in the gene is believed to cause a form of Parkinson's disease.

Application Notes

The optimal dilution of the anti-UchL1 antibody for each application should be determined by the researcher.

Immunogen

Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-UchL1 antibody.

Storage

Store the anti-UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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