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Home >> Antibodies >> Anti-TLR8 Antibody

Anti-TLR8 Antibody (F43434)

  Catalog No Formulation Size Price (USD)  
Image F43434-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F43434-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Anti-TLR8 antibody western blot analysis in NCI-H460 lysate. Expected molecular weight ~120 kDa.
Anti-TLR8 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NR97
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This anti-TLR8 antibody is available for research use only.
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Description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Application Notes

Titration of the anti-TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 434-463 from the human protein was used as the immunogen for this anti-TLR8 antibody.

Storage

Aliquot the anti-TLR8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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