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Home >> Antibodies >> Anti-TLR7 Antibody

Anti-TLR7 Antibody (F44379)

  Catalog No Formulation Size Price (USD)  
Image F44379-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F44379-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Anti-TLR7 antibody western blot analysis in Ramos lysate
IHC analysis of FFPE human hepatocarcinoma tissue stained with the anti-TLR7 antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9NYK1
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This anti-TLR7 antibody is available for research use only.
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Description

Toll like receptor 7 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). [UniProt]

Application Notes

Titration of the anti-TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 98-128 from the human protein was used as the immunogen for this anti-TLR7 antibody.

Storage

Aliquot the anti-TLR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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