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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Titration of the anti-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This anti-SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.
Aliquot the anti-SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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