- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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IgG antibody clone IG266 is a monoclonal antibody directed against immunoglobulin G, the most abundant antibody class in circulation and a central mediator of humoral immunity. IgG plays a critical role in pathogen neutralization, opsonization, complement activation, and long term immune memory. Because of its abundance and diverse functions, IgG detection is a standard component of immunology research, diagnostic assays, and therapeutic monitoring. NSJ Bioreagents provides IgG antibody clone IG266 for consistent, high quality detection of IgG across multiple applications.
IgG antibody clone IG266 is commonly used as a secondary or detection reagent in immunoassays. It recognizes the constant region of IgG molecules, enabling broad application across assays such as ELISA, western blotting, immunoprecipitation, and flow cytometry. The antibody reliably binds IgG without significant cross reactivity to other immunoglobulin classes, ensuring clean and interpretable results. Researchers rely on clone IG266 in both basic and applied settings where accurate quantification or identification of IgG is required.
In immunopathology, IgG antibody clone IG266 has been applied to tissue sections to investigate immune complex deposition, an important feature of autoimmune diseases including lupus nephritis and rheumatoid arthritis. Strong staining patterns produced by this antibody reveal the distribution of IgG in tissues and provide insight into how antibody mediated responses contribute to disease mechanisms.
In vaccine research and infectious disease studies, clone IG266 is used to measure antibody responses to antigens, confirming seroconversion and monitoring the development of protective immunity. Because IgG is the dominant isotype following secondary immune responses, detection with IgG antibody clone IG266 is essential for evaluating the durability of immunity.
The antibody has also been employed in therapeutic development, where engineered IgG antibodies are a leading class of biologic drugs. IgG antibody clone IG266 enables the detection and characterization of therapeutic antibodies, helping assess their stability, pharmacokinetics, and immune interactions.
Validated across immunohistochemistry, immunofluorescence, ELISA, and blotting applications, IgG antibody clone IG266 provides strong and reproducible signals. Its long publication history highlights its reliability and versatility. Alternate names include immunoglobulin G antibody, gamma globulin antibody, and Ig gamma antibody.
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the anti-IgG antibody to be titered up or down for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Purified human IgG heavy chain was used as the immunogen for this anti-IgG antibody.
Store the anti-IgG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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