- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Anti-HER2 Antibody (F50601)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F50601-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 429 | |
|
|
F50601-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 199 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P04626 |
| Applications | Western Blot : 1:1000 IHC (Paraffin) : 1:10-1:50 |
| Limitations | This anti-HER2 antibody is available for research use only. |
|
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HER2/ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Titration of the anti-HER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1227-1255 from the human protein was used as the immunogen for this anti-HER2 antibody.
Aliquot the anti-HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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