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- Email: info@nsjbio.com
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Titration of the anti-EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1004-1033 from the human protein was used as the immunogen for this anti-EGFR antibody.
Aliquot the anti-EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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