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Home >> Antibodies >> Anti-EGF Antibody

Anti-EGF Antibody (F47084)

  Catalog No Formulation Size Price (USD)  
Image F47084-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F47084-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Anti-EGF antibody western blot analysis in K562 lysate. Predicted band size : 134 kDa but routinely observed at 134-160kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P01133
Localization Cytoplasmic
Applications Western blot : 1:1000
Limitations This anti-EGF antibody is available for research use only.
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Description

This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.

Application Notes

Titration of the anti-EGF antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 940-967 from the human protein was used as the immunogen for this anti-EGF antibody.

Storage

Aliquot the anti-EGF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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