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Home >> Antibodies >> Anti-CXCR4 Antibody

Anti-CXCR4 Antibody (F47386)

  Catalog No Formulation Size Price (USD)  
Image F47386-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F47386-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Anti-CXCR4 antibody western blot analysis in NCI-H460 lysate. Predicted molecular weight ~40 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Bovine, Pig, Primate
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P61073
Applications Western blot : 1:1000
Limitations This anti-CXCR4 antibody is available for research use only.
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Description

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Application Notes

Titration of the anti-CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody.

Storage

Aliquot the anti-CXCR4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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