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Home >> Antibodies >> Anti-CD11c Antibody

Anti-CD11c Antibody [clone 428CT12.2.6.4] (F53616)

  Catalog No Formulation Size Price (USD)  
Image F53616-0.1ML In ascites with 0.09% sodium azide 0.1 ml 329
Anti-CD11c antibody western blot analysis in NCI-H292 lysate
Availability 1-3 business days
Species Reactivity Human
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 428CT12.2.6.4
Purity Ascites
UniProt P20702
Localization Cell surface, cytoplasmic
Applications Western blot : 1:500-1:2000
Limitations This anti-CD11c antibody is available for research use only.
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Description

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Application Notes

Titration of the anti-CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 246-274 from the human protein was used as the immunogen for this anti-CD11c antibody.

Storage

Aliquot the anti-CD11c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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