- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Anti-CD11c Antibody [clone 428CT12.2.6.4] (F53616)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53616-0.1ML | In ascites with 0.09% sodium azide | 0.1 ml | 369 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Ascites |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | 428CT12.2.6.4 |
| Purity | Ascites |
| UniProt | P20702 |
| Localization | Cell surface, cytoplasmic |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This anti-CD11c antibody is available for research use only. |
|
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This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Titration of the anti-CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 246-274 from the human protein was used as the immunogen for this anti-CD11c antibody.
Aliquot the anti-CD11c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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