- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Anti-Bcl-2 Antibody (F52104)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F52104-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F52104-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P10415 |
| Applications | Western blot : 1:1000 |
| Limitations | This anti-Bcl-2 antibody is available for research use only. |
|
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Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Titration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody.
Aliquot the anti-Bcl-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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