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Home >> Antibodies >> ANP Antibody / Atrial Natriuretic Peptide/Factor

ANP Antibody / Atrial Natriuretic Peptide/Factor (R31708)

  Catalog No Formulation Size Price (USD)  
Image R31708 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of ANP antibody and Lane 1: rat heart; 2: mouse heart lysate. Predicted molecular weight ~17kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 4878
Applications Western blot : 0.5-1ug/ml
Limitations This ANP antibody is available for research use only.
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Description

Atrial natriuretic peptide (ANP), also known as Atrial natriuretic factor (ANF), NPPA or PND, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. This gene is mapped to 1p36.22. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). ANP is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes) in response to high blood volume. It acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactly the opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodium in the kidney � that is, aldosterone stimulates sodium retention and it generates sodium loss.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the ANP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Atrial natriuretic peptide (SLRRSSCFGGRMDRIGAQSGLGCNSFRY) was used as the immunogen for this ANP antibody.

Storage

After reconstitution, the ANP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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