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Home >> Antibodies >> Annexin A2 Antibody / ANXA2

Annexin A2 Antibody / ANXA2 (R30414)

  Catalog No Formulation Size Price (USD)  
Image R30414 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of Annexin A2 antibody and Lane 1: rat testis; 2: rat lung; 3: rat ovary; 4: MCF-7; 5: SMMC-7721; 6: A549; 7: Jurkat
IHC-P: Annexin A2 antibody testing of human intestinal cancer tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P07355
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
IHC (Frozen) : 0.5-1ug/ml
Limitations This Annexin A2 antibody is available for research use only.
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Description

Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al.(1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Annexin A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the middle region of human Annexin A2 (RAEDGSVIDYELIDQDARDLY) was used as the immunogen for this Annexin A2 antibody.

Storage

After reconstitution, the Annexin A2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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