- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Annexin A1 Antibody for WB / ANXA1 Western Blot Antibody is a mouse monoclonal antibody, clone CPTC-ANXA1-1, targeting Annexin A1, a calcium-dependent phospholipid-binding protein encoded by the ANXA1 gene. Annexin A1 belongs to the annexin family and has a predicted molecular weight of approximately 39 kDa. The protein participates in membrane-associated processes, inflammatory regulation, cell signaling and responses to cellular stress, making ANXA1 relevant to research spanning immunology, inflammation and cancer biology.
Annexin A1 was historically characterized as lipocortin I because of its association with glucocorticoid-mediated anti-inflammatory effects. ANXA1 can regulate leukocyte activity and inflammatory responses and has been studied in processes involving neutrophil migration, macrophage function and resolution of inflammation. Its functions are influenced by cellular localization, phosphorylation, proteolytic processing and interactions with membranes and signaling proteins. An Annexin A1 Antibody for WB can support analysis of ANXA1 abundance and molecular weight patterns across different tissues, cell types and experimental conditions.
ANXA1 is also extensively investigated in cancer research. Altered Annexin A1 expression has been reported in multiple malignancies, although its relationship with tumor biology can vary according to tissue and cellular context. Research has connected ANXA1 with cellular proliferation, migration, invasion, differentiation and interactions between tumor cells and the surrounding microenvironment. These diverse functions make analysis of Annexin A1 protein expression relevant to studies of both normal cellular physiology and disease-associated signaling.
Western blot analysis commonly detects Annexin A1 near its expected molecular weight of approximately 39 kDa. Additional immunoreactive species in the neighboring molecular weight range may also be observed depending on sample type and experimental conditions. Annexin A1 is known to undergo post-translational modification and proteolytic processing, particularly involving its N-terminal region, which can contribute to molecular heterogeneity. Clone CPTC-ANXA1-1 has demonstrated Western blot detection across human cells and tissues as well as samples from multiple mammalian species, providing useful data for comparative ANXA1 expression studies.
NSJ Bioreagents offers mouse monoclonal Annexin A1 Antibody clone CPTC-ANXA1-1 for Western blot-based investigation of ANXA1 expression. An ANXA1 Western Blot Antibody can support research into inflammatory regulation, immune signaling, membrane biology, cellular stress and cancer-associated changes in Annexin A1 expression.
Researchers studying Annexin A1 expression and function can explore our Protein Microarray Validated Annexin A1 Antibody page for additional reagents targeting ANXA1 in inflammatory signaling, immune regulation and cancer biology.
Optimal dilution of the Annexin A1 Antibody for WB / ANXA1 Western Blot Antibody to be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Recombinant full-length human protein was used as the immunogen for the Annexin A1 antibody.
Store the Annexin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Annexin A1 antibody, ANXA1 antibody, ANXA1 Western Blot antibody, Annexin A1 Western Blot antibody, Annexin A1 Antibody for WB, Lipocortin I antibody, Lipocortin 1 antibody, Annexin I antibody, Calpactin II antibody
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